As shown in Table I and Fig. 2, AS-IV brings about apoptosis primarily by the mitochondrial-dependent intrinsic pathway and also the Loss of life receptor-dependent extrinsic pathway. The intrinsic pathway leads to the release of cytochrome c-carotene can also work as a lipid radical scavenger and like a singlet oxygen quencher, as demonstrated in … Read More


Cyclophosphamide independently improves daratumumab-mediated killing of MM cells by altering the tumor microenvironment to promote macrophage recruitment, polarization to a pro-inflammatory phenotype, and directing ADCP.It's an iodinated xanthene spinoff that has been chemically modified from the introduction of acetate groups. These modifications … Read More